Similarly, in the comparison between Group first and Group second (thrombus group) Table 1, the variables of permanent AF, heart failure, history of stroke, BNP, uric acid, and D-dimer, Mitral regurgitation, LVEF, LVED, LAD, CHA2DS2-VASc score, Left atrial appendage filling velocity, Left atrial appendage emptying rate also demonstrated statistical significance (p < 0.05). The gene discussed is NPPB; the disease is atrial fibrillation.