In hospitalized patients with OPFs, we observed a negative linear association between CCR and mortality after adjusting for confounding factors, including PT, APTT, platelet count, hemoglobin, albumin, calcium, neutrophils, lymphocytes, monocytes, potassium, uric acid, ASA category, hypertension, diabetes, tumor, shock, and smoking (Figure 3). This evidence concerns the gene ALB and hypertensive disorder.