They significantly impact retinal diseases like diabetic retinopathy (DR) and retinopathy of prematurity (ROP), influencing key pathological processes: inflammation (e.g., HOTAIR, SNHG16), apoptosis (MEG3, HOTTIP), and angiogenesis (MALAT1, MIAT, ANRIL).51 Here, HOTTIP is linked to retinopathy of prematurity.