TGFB1 and Hepatic fibrosis: Luteolin, as found in many identified peaks (8, 37, 38, 39 & 41), was reported to suppress the progression of liver fibrosis in four animal models induced by CCl4, DMN, BDL, and thioacetamide directing AKT/mTOR/p70S6K, PI3K/Akt pathways and TGFβ/Smad signaling pathways [77,78].