The AUC of IGFBP6 for differential diagnosis of sepsis and non-septic infection was 0.67 (95% CI, 0.57 to 0.78) (Supplemental Figure 2B) and 0.78 (95% CI, 0.73 to 0.84) (Supplemental Figure 2D), respectively. Here, IGFBP6 is linked to infection.