MCL1 and melanoma: It was discovered that the specific Mcl-1 protein inhibitor - MIM1 i/ decreases C32 cells viability, ii/ induces apoptosis (shown as cell-cycle modulatory effect - S-phase arrest, DNA fragmentation as well as redox imbalance – decrease of intracellular GSH level) in amelanotic melanoma cells and iii/ intensifies the proapoptotic properties of dacarbazine, as a result of interactions with Mcl-1 protein [5].