On the other hand, it was observed that the MIM1/temozolomide mixture exhibited a greater cytotoxic effect on U87MG glioblastoma cells than MIM1 alone, providing for the first time convincing evidence that MIM1, which inhibits Mcl-1 antiapoptotic protein, can sensitize glioblastoma cells to alkylating agents. The gene discussed is MIMT1; the disease is glioblastoma.