No alterations in the genes APC, AXIN1, AXIN2, BRAF, NRAS, HRAS, KRAS, EIF1AX, PTEN, TERT, PI3KCA, KMT2C, KMT2D, CHEK2, ATM, and TP53 were detected in any of the samples from the main nodule, thyroid adenoma, or “normal” thyroid. Here, AXIN2 is linked to Thyroid adenoma.