TARDBP and amyotrophic lateral sclerosis: Irrespective of sporadic or familial forms, protein inclusions composed of hyperphosphorylated, ubiquitinated and N‐terminally truncated TDP‐43 [42, 43, 44] are a hallmark of the bulk of ALS patients [11, 45] and nearly 50% of all FTLD cases [46, 47].