In yet another effort for a continued search for novel pathways that participate in these diseases, genetic interaction between ALYREF, a component of mRNA nuclear export complex [282], whose levels in ALS patient motor neurons with TDP‐43 pathology are altered [283], and an interaction partner of MSUT‐2, a suppressor identified in a genetic screen in a C. elegans tauopathy model [284], was tested. Here, ALYREF is linked to tauopathy.