SMOX and cystic fibrosis: To biochemically assess the ability of the PA0884-PA0886 TRAP system in PAO1 to recognise dicarboxylates relevant to colonisation of the CF lung, we assessed their binding to recombinantly expressed IctP (PA0884) (Supplementary Figure–S1), the SBP of the transport system, using nano differential scanning fluorimetry (nanoDSF) (Figure 2A).