IL10 and rheumatoid arthritis: fMSC-EVs treated cells dominated the comparative canonical pathway list with inhibition of various proinflammatory pathways such as the “role of chondrocytes in rheumatoid arthritis” and “osteoarthritis” pathways and activation of the “IL-10” and “extracellular matrix organization” pathways (Fig. 6, Table S8, for individual molecules responsible for the activation or inhibition of specific pathways see Tables S13-S16).