ATF6 and colorectal cancer: To investigate a potentially dissimilar effect of ATF6 expression in individuals with early-onset colorectal cancer (age < 50 years; EOCRC) versus late-onset colorectal cancer (age > 50 years; LOCRC), we quantified ATF6 expression in additional individuals from cohort 3 with EOCRC (cohort 3; n = 55 EOCRC).