We next integrated differentially regulated transcripts with the transcriptomic profiles of patient samples from MMRF CoMMpass study (NCT01454297) and identified an uncharacterized lncRNA—LINC02362 (termed as PLUM) associated with NF-κB mutant, high-risk MM subtypes (Fig. 1a). Here, NFKB1 is linked to Miyoshi myopathy.