We focused specifically on two regions: (i) the medial temporal lobe, including the hippocampus; and (ii) the thalamus, including the PVT, to investigate the accumulation of major neurodegenerative disease–associated proteins, phosphorylated tau, amyloid‐β, α‐synuclein, and TDP‐43. The gene discussed is MAPT; the disease is neurodegenerative disease.