C9orf3, a gene previously identified in PCOS GWAS (Chen et al. 2011, Shi et al. 2012, Hayes et al. 2015, Day et al. 2018), and BMP6, which plays a role in folliculogenesis by regulating granulosa cell function (Shi et al. 2011) and is overexpressed in individuals with PCOS (Khalaf et al. 2013), were among the strongest associations. Here, AOPEP is linked to polycystic ovary syndrome.