Nonetheless, the results shown that Rag1−/− mice repopulated with Atg7ΔCD4CD4+ T cells exhibited more pronounced colitis symptoms, including greater weight reduction, shorter colon length, higher disease activity index, pathological scores and MPO activity, in contrast to mice repopulated with Atg7fl/flCD4+ T cells (Figure 5A–G). This evidence concerns the gene MPO and colitis.