免疫表型:表达CD19,特征为CD5和CD23与CD19共表达,CD200在CLL中高表达,表达ROR1,但CD20和sIg弱表达,FMC7、CD22和CD79b常阴性或弱表达,不表达cyclin D1(免疫组化,IHC)与CD10。通常表达LEF1(IHC)。. The gene discussed is CD5; the disease is B-cell chronic lymphocytic leukemia.