CRP and obesity due to melanocortin 4 receptor deficiency: CRP concentrations at 12, 28 GW increased with higher BMI (for normal weight, overweight, and obesity, respectively: 12 GW 4.12 vs 6.68 vs 11.7 mg/L, P < 0.001; 28 GW 4.45 vs 6.87 vs 9.70 mg/L, P < 0.001).