IL6 and obesity due to melanocortin 4 receptor deficiency: At 12 and 28 GW, women with obesity had higher IL-6 concentrations compared with normal weight women (12 GW 2169 vs 1371 fg/mL, P = 0.004; 28 GW 2251 vs 1460 fg/mL, P = 0.021 in obesity and normal weight, respectively).