CD4 and neoplasm: In prostate cancer, Wang et al. (2019) [75] demonstrated a strong correlation between UBASH3B expression and tumor-infiltrating immune cells, including B cells, CD4 + memory T-cells, regulatory T-cells, activated NK cells, M2 macrophages, dendritic cells, resting mast cells, and neutrophils, thus suggesting a role of UBASH3B in modulating the tumor immune microenvironment.