As illustrated in Figure S2, SIRT7 exhibited superior diagnostic accuracy (AUC: 0.917, 95% CI 0.882–0.951) for distinguishing hypertension in conjunction with CAD compared to CK (AUC: 0.698, 95% CI 0.629–0.768 P < 0.001), CK-MB (AUC: 0.814, 95% CI 0.750–0.879 P < 0.001) and HDL-C (AUC: 0.674, 95% CI 0.604–0.745 P < 0.001). Here, SIRT7 is linked to Hypertension.