A screen for secondary causes of osteoporosis was unremarkable ((Corrected Calcium (calculated as total calcium (mmol/L) + [(40- albumin (g/L)) × 0.02] was 2.49 mmol/L (laboratory reference range 2.1–2.6), Phosphate 1.07 mmol/L (0.8–1.5), Creatinine 47 μmol/L (45–90), 25(OH)D 65 nmol/L (> 50, DiaSorin Liaison XL immunoassay), eosinophils 0.4 × 10^9/L (< 0.7) and TSH 1.18 mU/L (0.4–4.0). The gene discussed is ALB; the disease is osteoporosis.