Additionally, while tail‐vein injection models are widely used for assessing post‐intravasation metastasis, they do not capture the full metastatic cascade, including primary tumor EMT and intravasation.[51] Incorporating spontaneous metastasis model, in which cancer cells naturally undergo hypoxia‐driven EMT, intravasation, and distant organ seeding,[51] would provide more robust mechanistic validation of the hypoxia‐induced PRMT1‐vimentin pathway. Here, VIM is linked to cancer.