LCN2, known as neutrophil gelatinase‐associated lipocalin, is expressed in various tissues and cell types.[44] It functions as both an intracellular and secreted protein and has been widely studied for its diverse and complex functions in multiple diseases, including cancers.[24] However, different studies on LCN2 have reported conflicting conclusions regarding its role in tumor progression and metastasis. The gene discussed is LCN2; the disease is cancer.