A selection of the top 200 proteins expressed in correlation with one of the three CTLH members in both types of tumors revealed that the overlapping proteins favor the comparisons RANBP10 LUAD vs RANBP10 LUSQ, RANBP9 LUAD vs RANBP9 LUSQ, and GID8 LUAD vs GID8 LUSQ, suggesting strongly concordant effects on tumor biology across distinct tumor histologies (Fig. 6G, I). The gene discussed is GID8; the disease is neoplasm.