CD274 and non-small cell lung carcinoma: As core features of NSCLC, the rearrangement of glucose metabolism and immune escape (PD-L1 expression) have a mutually positive regulatory relationship, significantly influencing the biological behavior of tumors.13,14,28 Parameters of FDG PET/CT, a non-invasive routine assessment method, can effectively reflect the glycometabolic status and morphological features of LA-NSCLC, making them ideal PD-L1 predictive markers.