miRNA 27a-3p is involved in the retinoblastoma progression56, in the promotion of cerebral ischemia/reperfusion injury57, in the modification of hypoxia-induced malignant behaviors of glioma cells58, in the neurotoxicity induced by anesthetic administration59, in the multi-drug resistance P-glycoprotein in blood-brain barrier60 and in the promotion of neurofibromatosis61. Here, ABCB1 is linked to brain ischemia.