NR4A1 and neoplasm: High levels of H&E sTILs (≥10%) were observed in 53% of tumors (mean = 17%, median = 10%, IQR, 5–20%) (Table 1 and Supplementary Fig. S2); these cases demonstrated a significant association with aggressive pathological features including tumor size >2 cm, grade III, axillary nodal positivity and hormone receptor-negative status (P < 0.05).