To investigate whether the immunomodulation of γδ T cells by PDOs is a generalizable phenomenon of colorectal cancer–γδ T-cell interactions, we performed an additional phenoscaping study of stIL15-γδ T cells from x4 proliferative and cytotoxic donors (A, B, E, and G; Supplementary Fig. S5A; Figs. 1D, E, and 2C and D) ± ×10 different colorectal cancer PDOs, ± anti-B7-H3 mAb (Fig. 3A). This evidence concerns the gene CD276 and colorectal cancer.