Statistically significant findings (p < 0.05) are marked with an asterisk. 6MWD, 6-minute walking distance; Alb, albumin; ADPKD, autosomal dominant polycystic kidney disease; CCI, Charlson comorbidity index; Cre, creatinine; eGFR, estimated glomerular filtration rate; EQ-5D-5L, EuroQol 5-Dimension 5-Level; EQ-VAS, EuroQol visual analogue scale; Hb, hemoglobin; IgA, immunoglobulin A; IPAQ, International Physical Activity Questionnaire-Short Form; METs, metabolic equivalents; SMI, skeletal muscle mass index; TUG, Timed Up & Go test. Here, GSTM1 is linked to autosomal dominant polycystic kidney disease.