ERBB2 and metastatic malignant neoplasm in the lymph nodes: Numerous variables, including tumor size, histologic type, histologic grade, age at diagnosis, pTNM (pathological Tumor, Node, Metastasis) staging, lymph node metastasis, and molecular profiles (such as the p53 gene, human epidermal growth factor receptor 2/neu (HER2/neu), and others), influence the prediction of breast cancer [1,6].