CRP and non-small cell lung carcinoma: While previous research in NSCLC has identified lower baseline levels of NLR, PLR, CRP, CXCL9, CXCL10, CXCL11, and CXCL19 as associated with irAEs (2), some inflammatory markers, such as C-reactive protein (CRP) and IL-6, were not routinely measured in this cohort, potentially introducing selection bias.