We observed that acute exercise reduced the expression of genes involved in the MHC I-mediated antigen processing and presentation pathway (ASB13, CD14, CTSL, CYBB, NCF2, RNF144B, S100A9, TLR2, UBE2E2) in the NK cells from children with ALL in remission, but not in the controls (Supplementary Tables S6, S7). Here, CTSL is linked to acute lymphoblastic leukemia.