Several genes involved in IL-2 family signaling (HAVCR2, IL3RA, INPP5J), Glucocorticoid Receptor Signaling (ANXA1, AR, HLA-DQA1, IFNLR1, IL3RA, IL4, KRT1, MMP1, MT-ND3, MT-ND6, RARB, SDHA), PI3K/AKT Signaling (IFNLR1, IL3RA, INPP5J, ITGAD, YWHAQ), and molecular mechanisms of cancer (ADGRA3, C5AR2, CDKN2C, CTNNA1, GPR173, GPR183, IFNLR1, IL3RA, ITGAD, MMP1, PTGDR2, PTGER3, RBL1) were differently expressed in NK cells from children with ALL in remission compared to controls (Table 2, Supplementary Tables S1, S2). This evidence concerns the gene ADGRA3 and acute lymphoblastic leukemia.