IL1B was reduced after acute exercise in NK cells of children with ALL in remission but not in controls (log2FC -1.68 vs. -0.18; p<0.001 and p=0.59 respectively, [Supplementary Tables S6, S7) and it was the gene with the higher number of connections within the interactive gene network enriched in inflammatory response (Figure 5). Here, IL1B is linked to acute lymphoblastic leukemia.