The previous study also identified miRNAs, including hsa-mir-155-5p, hsa-miR-192-5p, hsa-miR-124-5p, hsa-miR-335-5p, hsa-mir-34a-5p, and miR-7110, as well as TFs, including Smad5 and Bcl6, that may be beneficial for the diagnosis and management of T2DM [68–70]. The gene discussed is SMAD5; the disease is type 2 diabetes mellitus.