By designing a mouse model, it was found that Dendrobium polysaccharides were able to ameliorate functional abnormalities caused by myocardial fibrosis by restoring the activity of aquaporin-5 through the inhibition of lymphocyte infiltration, as well as release of inflammatory factors and apoptosis caused by lymphocyte infiltration (229). This evidence concerns the gene AQP5 and Myocardial fibrosis.