Moreover, as a member of the B7 family of immunoregulatory molecules, B7-H3 is also expressed on various immune cells, including macrophages, monocytes, dendritic cells, myeloid-derived suppressor cells (MDSCs), and some T cell subsets, where it contributes to immune evasion and tumor progression by modulating the local immune landscape within the tumor microenvironment [36, 37]. Here, CD276 is linked to neoplasm.