Specifically, we found a positive correlation with neutrophil and monocyte infiltration, yet a negative correlation with CD4+, CD8+ T cells, and DCs across a broad spectrum of cancers, including KIRC, THCA, THYM, BRCA, LAML, PRAD, COAD, HNSC, LIHC, LUAD, STAD, and LGG. This evidence concerns the gene CD8A and cancer.