The analysis of immune infiltration concerning the MGAM and MGAM2 genes revealed an overall positive correlation with neutrophil and monocyte infiltration while exhibiting a negative correlation with CD4+, CD8+ T cells, and DC cells across various cancers such as KIRC, THCA, THYM, BRCA, LAML, PRAD, COAD, HNSC, LIHC, LUAD, STAD, and LGG. The gene discussed is CD8A; the disease is cancer.