Among the differentially expressed genes between the MC and HD groups, genes such as Hspa1a, Dusp1, JunD, and Gsdma2 in the HD group showed low expression, whereas genes such as Cyp1a1, Slc15a2, Ccr4, and Slfn1 showed high expression (Figure 4C). Here, DUSP1 is linked to Huntington disease.