According to the Kaplan-Meier Plotter analysis, increased levels of NPC1 expression were significantly correlated with lower OS [P = 1e-04, HR = 1.99 (1.4–2.84)], RFS [P = 0.0064, HR = 1.61 (1.14–2.27)], and disease-free survival (DFS) [P = 0.00089, HR = 2.12 (1.35–3.35)] in patients with liver cancer (Figure 2C). Here, NPC1 is linked to liver cancer.