NPC1 and cancer: Furthermore, we extended to other cancer types using the Kaplan-Meier plotter database, which showed that high levels of NPC1 expression were linked to poorer OS in patients with Bladder carcinoma, Cervical squamous cell carcinoma, Esophageal carcinoma, Kidney carcinoma, Ovarian cancer, lung carcinoma, Hepatocellular carcinoma,and Pancreatic ductal adenocarcinoma (Supplementary Figure S1).