APP (4 references; q = 0.00832), NLRP3 (5 references; q = 0.00229), and PVT1 (8 references; q = 0.00229) are positively regulated in HNSCC, whereas CYP2C19 is negatively regulated (4 references; q = 0.00832). The gene discussed is NLRP3; the disease is head and neck squamous cell carcinoma.