To further explore the mechanisms and molecular interactions involved in ASCC3 within the tumor microenvironment, we analyzed the differences in ASCC3 expression across 14 tumor-associated signaling pathways, including androgen, EGFR, estrogen, hypoxia, JAK-STAT, MAPK, NF-κB, p53, PI3K, TGF-β, TNF-α, TRAIL, VEGF and WNT signaling pathways. The gene discussed is VEGFA; the disease is neoplasm.