Chronic inflammation induced by infection can promote the release of pro-inflammatory cytokines such as IL-6 and TNF-α, leading to insulin resistance (IR), hepatic very-low-density lipoprotein (VLDL) overproduction (7), and suppression of lipoprotein lipase (LPL) activity, thereby impairing TG clearance (8). The gene discussed is IL6; the disease is infection.