Western blot analysis revealed that treatment with Polydatin (50 mg/kg/day for 1 week) significantly reduced the protein expression of BDNF and NRG-1 in the sympathetic ganglia compared to untreated hyperhidrosis mice (p = 0.009 and p = 0.035, respectively; Figures 3A–C). This evidence concerns the gene NRG1 and Hyperhidrosis.