Increased GLUT expression has been demonstrated to directly inhibit the expression of E-cadherin in bronchial cells in asthma (Lv et al., 2024), promote the expression of vascular endothelial growth factor A in epithelial cells in ARDS (Liang et al., 2024), and activate the mTOR signaling pathway to exacerbate lung fibrosis (Andrianifahanana et al., 2016). The gene discussed is SLC2A1; the disease is acute respiratory distress syndrome.