All proteins selected by PLSKO have been reported to be related to preeclampsia, including SERPINE1 (Zhao et al. 2013), HSPB1 (Martin et al. 2022), CXCL10 (Gotsch et al. 2007), DKK1 (Kasoha et al. 2021). The gene discussed is CXCL10; the disease is preeclampsia.