COL3A1 and Ehlers-Danlos syndrome, vascular type: Vascular Ehlers‐Danlos syndrome (vEDS, MIM # 130050) is a rare condition characterized by vascular and tissue fragility, with high mortality due to an alteration in the COL3A1 gene, which encodes the pro‐α1 chains of type III procollagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine, and the vascular system, frequently in association with type I collagen.4, 5