PA were assessed using the MDS-UPDRS-III item 3.13 and risk factors were analyzed with Cox uncertain regression.<h4>Results</h4>SNCA-PD patients were the youngest at onset (50.8 years) and showed the highest PA cumulative incidence over 4 years (30%), followed by GBA-PD (25.8%), idiopathic PD (23%), and LRRK2-PD (17.2%). This evidence concerns the gene GBA1 and Parkinson disease.