Transcriptome results identified many DEGs linked to insulin resistance, fatty acid β oxidation, and inflammation, including IGF2BP2, LEPR, RAP1A, SESTRIN 3, and ITLN1 that have also been reported in human T2DM (Lee et al., 2008; Su et al., 2016; Zhao et al., 2014; Nascimento et al., 2013; Tabassum et al., 2012). Here, SESN3 is linked to Insulin resistance.