Several of these genes have been reported as correlated with T2DM in humans, including IGF2BP2, LEPR, RAP1A, SESTRIN 3, and ITLN1 (Lee et al., 2008; Su et al., 2016; Zhao et al., 2014; Nascimento et al., 2013; Tabassum et al., 2012). This evidence concerns the gene SESN3 and type 2 diabetes mellitus.