IL1B and epilepsy: Brain inflammation in epilepsy is primarily characterized by the proinflammatory mediators in the epileptic focus [10], such as interleukin‐1β (IL‐1β) [11, 12], high‐mobility group box 1 (HMGB1) [13, 14, 15], and tumor necrosis factor‐α (TNF‐α) [16, 17].