Using the criteria P-SMR-multi <0.05, P-SMR<0.05 and P-HEIDI>0.01, we identified seven proteins (Apolipoprotein B (APOB), Glucose-6-Phosphate Dehydrogenase (G6PD), Heat Shock Transcription Factor 1(HSF1), Insulin Like Growth Factor 1 Receptor (IGF1R), Protein Kinase C Beta (PRKCB), Ras-related protein Rab-1A (RAB1A), Signal Regulatory Protein alpha (SIRPA)) corresponding to genes associated with T2DM. The gene discussed is SIRPA; the disease is type 2 diabetes mellitus.