ROCK2 and epilepsy: The ROCK1 is predominantly expressed in nonneuronal tissues such as the liver, testes, and kidneys, while the ROCK2 is primarily found in the brain and skeletal muscle.[67, 68] Importantly, studies have documented decreased expression of RhoA and ROCK1 but an increase in ROCK2 in a rat model of epilepsy,[69] suggesting subtype‐specific roles in epilepsy.