Conversely, epidermal overexpression of Fads2 via AAV‐K14‐flag‐Fads2 delivery led to a marked upregulation of both FADS2 mRNA and protein levels (Figure S3C,D, Supporting Information), and markedly alleviated IMQ‐induced psoriasis‐like inflammation (Figure 4J). Here, KRT14 is linked to psoriasis.